Concepedia

Dihydropyrimidine dehydrogenase activity in cancer patients

G. Milano, M Gaspard, A. Thyss, N. Renée, M. Schneider, F Démard, Ronald A. Fleming, P.J. Bargnoux, R Plagne

European Journal of Cancer · 1993 · 85 citations · 21 references

DOI

Concepts

References

21

Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase activity.

Richard M. Weinshilboum, S. L. Sladek · PubMed · 1980 · 1.2K citations

, , +13

Clinical pharmacokinetics of 5-fluorouracil and its metabolites in plasma, urine, and bile.

Glen D. Heggie, Jean‐Pierre Sommadossi, David S. Cross et al. · PubMed · 1987 · 731 citations

, , +17

Cancer Chemotherapy: Principles and Practice

Annals of Internal Medicine · 1990 · 572 citations

, , +12

Familial deficiency of dihydropyrimidine dehydrogenase. Biochemical basis for familial pyrimidinemia and severe 5-fluorouracil-induced toxicity.

Robert B. Diasio, T L Beavers, John T. Carpenter · Journal of Clinical Investigation · 1988 · 500 citations · Full text

, , +14

Relationship between dihydropyrimidine dehydrogenase activity and plasma 5-fluorouracil levels with evidence for circadian variation of enzyme activity and plasma drug levels in cancer patients receiving 5-fluorouracil by protracted continuous infusion.

Barry Harris, Seng-Jaw Soong, Robert B. Diasio · PubMed · 1990 · 445 citations

, , +17