Concepedia

Cytochrome P-450 activities in human and rat brain microsomes

Pierre Voirol, Michèle Jonzier-Perey, François Porchet, Marianne J. Reymond, Robert C. Janzer, Constantin Bouras, Henry W. Strobel, Markus Kosel, Chin B. Eap, Pierre Baumann

Brain Research · 2000 · 79 citations · 39 references

DOI

Concepts

References

39

Differential selectivity of cytochrome P450 inhibitors against probe substrates in human and rat liver microsomes

Victoria A. Eagling, John Tjia, David Back · British Journal of Clinical Pharmacology · 1998 · 334 citations · Full text

Five Distinct Human Cytochromes Mediate Amitriptyline N‐Demethylation<i>In Vitro</i>: Dominance of CYP 2C19 and 3A4

Karthik Venkatakrishnan, David J. Greenblatt, Lisa L. von Moltke et al. · The Journal of Clinical Pharmacology · 1998 · 155 citations

Polymorphic Drug Oxidation

Leif Bertilsson, Marja­‐Liisa Dahl · CNS Drugs · 1996 · 140 citations

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MPTP, the neurotoxin inducing parkinson's disease, is a potent competitive inhibitor of human and rat cytochrome P450 isozymes (P450bufI, P450db1) catalyzing debrisoquine 4-hydroxylation

Raymonde Fonné‐Pfister, Mario Bargetzi, Urs Meyer · Biochemical and Biophysical Research Communications · 1987 · 129 citations

, , +9

Human cytochrome P450 3A (CYP3A) mediated midazolam metabolism

Jukka M enp, Stephen D. Hall, Barbara J. Ring et al. · Pharmacogenetics · 1998 · 118 citations

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