Enhanced protein thermostability from designed mutations that interact with α-helix dipoles

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

Thomas A. Kunkel, John D. Roberts, Richard A. Zakour · Methods in enzymology on CD-ROM/Methods in enzymology · 1987 · 5.3K citations

Efficient Site-specific Mutagenesis, Genetics, Directed Evolution +5

Amino Acid Preferences for Specific Locations at the Ends of α Helices

Jane S. Richardson, David Richardson · Science · 1988 · 1.4K citations

Protein stability curves

Wayne J. Becktel, John A. Schellman · Biopolymers · 1987 · 1K citations

Stability Curves, Protein Stability Curves, Free Energy +14

The α-helix dipole and the properties of proteins

Wim G. J. Hol, P.Th. van Duijnen, H. J. C. Berendsen · Nature · 1978 · 994 citations

Protein Chemistry, Biochemistry, Protein Assembly +8

Oligonucleotide-Directed Mutagenesis: A Simple Method Using Two Oligonucleotide Primers and a Single-Stranded DNA Template

Mark J. Zoller, Michael J. Smith · DNA · 1984 · 906 citations