Deletion of Irf5 protects hematopoietic stem cells from DNA damage-induced apoptosis and suppresses γ-irradiation-induced thymic lymphomagenesis

Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors

Akinori Takaoka, Hideyuki Yanai, Seiji Kondo et al. · Nature · 2005 · 1K citations

Inflammation, Toll-like Receptors, Cytokine +11

Slug Antagonizes p53-Mediated Apoptosis of Hematopoietic Progenitors by Repressing puma

Wen-Shu Wu, Stefan Heinrichs, Dong Xu et al. · Cell · 2005 · 400 citations · Full text

Hematopoietic Progenitors, Apoptosis, Pathology +4

The Interferon Regulatory Factor, IRF5, Is a Central Mediator of Toll-like Receptor 7 Signaling

Annett Schoenemeyer, Betsy Barnes, Margo E. Mancl et al. · Journal of Biological Chemistry · 2005 · 397 citations · Full text

Innate Immune System, Immunology, Immunologic Mechanism +20

Virus-specific Activation of a Novel Interferon Regulatory Factor, IRF-5, Results in the Induction of Distinct Interferon α Genes

Betsy Barnes, Paul A. Moore, Paula M. Pitha · Journal of Biological Chemistry · 2001 · 386 citations · Full text

p53-deficient mice are extremely susceptible to radiation-induced tumorigenesis

Christopher J. Kemp, Tom E. Wheldon, Allan Balmain · Nature Genetics · 1994 · 369 citations

P53-deficient Mice, Radiation Therapy, Radiation Effect +6