Specificity, location and function of βTrCP isoforms and their splice variants

The SCFbeta -TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in Ikappa Balpha and beta -catenin and stimulates Ikappa Balpha ubiquitination in vitro

Jeffrey Winston, Peter R. Strack, Peggy Beer‐Romero et al. · Genes & Development · 1999 · 941 citations · Full text

The F-box protein β-TrCP associates with phosphorylated β-catenin and regulates its activity in the cell

Matthew J. Hart, Jean‐Paul Concordet, Irina Lassot et al. · Current Biology · 1999 · 667 citations · Full text

Transcriptional Regulation, Signal Transduction, Signaling Pathway +10

A Novel Human WD Protein, h-βTrCP, that Interacts with HIV-1 Vpu Connects CD4 to the ER Degradation Pathway through an F-Box Motif

Florence Margottin-Goguet, Stephan Bour, Hervé Durand et al. · Molecular Cell · 1998 · 658 citations

Signal Transduction, Human Retrovirus, Immunology +8

Structure of a β-TrCP1-Skp1-β-Catenin Complex

Geng Wu, Guozhou Xu, Brenda A. Schulman et al. · Molecular Cell · 2003 · 601 citations · Full text

Molecular Complex, Structural Biology, Molecular Biology +1

M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCF ^β-TrCP

Nobumoto Watanabe, Harumi Arai, Yoshifumi Nishihara et al. · Proceedings of the National Academy of Sciences · 2004 · 464 citations · Full text

Molecular Regulation, Molecular Biology, Beta-trcp Recognition +19