Florence Margottin-Goguet

SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates

Hichem Lahouassa, Waaqo Daddacha, Henning Hofmann et al. · Nature Immunology · 2012 · 818 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +13

A Novel Human WD Protein, h-βTrCP, that Interacts with HIV-1 Vpu Connects CD4 to the ER Degradation Pathway through an F-Box Motif

Florence Margottin-Goguet, Stephan Bour, Hervé Durand et al. · Molecular Cell · 1998 · 659 citations

Life Sciences, Biochemistry, Molecular Biology +7

Control of Meiotic and Mitotic Progression by the F Box Protein β-Trcp1 In Vivo

Daniele Guardavaccaro, Yasusei Kudo, Jérôme Boulaire et al. · Developmental Cell · 2003 · 353 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Prophase Destruction of Emi1 by the SCFβTrCP/Slimb Ubiquitin Ligase Activates the Anaphase Promoting Complex to Allow Progression beyond Prometaphase

Florence Margottin-Goguet, Jerry Y. Hsu, Alexander V. Loktev et al. · Developmental Cell · 2003 · 335 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12

Vpu Antagonizes BST-2–Mediated Restriction of HIV-1 Release via β-TrCP and Endo-Lysosomal Trafficking

Richard S. Mitchell, Chris Katsura, Mark Skasko et al. · PLoS Pathogens · 2009 · 317 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17