Concepedia

Curcumin attenuates diabetic nephropathy by inhibiting PKC‐α and PKC‐β<sub>1</sub> activity in streptozotocin‐induced type I diabetic rats

Vivian Soetikno, Kenichi Watanabe, Flori R. Sari, Meilei Harima, Rajarajan A. Thandavarayan, Punniyakoti T. Veeraveedu, Wawaimuli Arozal, Vijayakumar Sukumaran, Arun Prasath Lakshmanan, Somasundaram Arumugam,

Molecular Nutrition & Food Research · 2011 · 128 citations · 38 references

DOI

Abstract

These results prove that curcumin produces dual blockade of both PKC-α and PKC-β1 activities, which suggests that curcumin is a potential adjuvant therapy for the prevention and treatment of diabetic nephropathy.

References

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