Innate Immune Activation and CD4+ T Cell Priming during Respiratory Fungal Infection

Cloning of a new cytokine that induces IFN-γ production by T cells

Haruki Okamura, Hiroko Tsutsui, Toshinori Komatsu et al. · Nature · 1995 · 2.6K citations

Immune Cell Development, Immunology, Immune Regulation +10

Targeted Disruption of the MyD88 Gene Results in Loss of IL-1- and IL-18-Mediated Function

Osamu Adachi, Taro Kawai, Kiyoshi Takeda et al. · Immunity · 1998 · 2K citations · Full text

Inflammation, Cytokine, Immunogenetics +11

Toll-like receptors control activation of adaptive immune responses

Markus Schnare, Gregory M. Barton, Agnieszka Czopik Holt et al. · Nature Immunology · 2001 · 1.4K citations

Inflammation, Toll-like Receptors, Innate Immune System +7

Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

Kasper Hoebe, Xin Du, Philippe Georgel et al. · Nature · 2003 · 1.2K citations

Molecular Physiology, Signal Transduction, Natural Sciences +8

IGIF Does Not Drive Th1 Development but Synergizes with IL-12 for Interferon-γ Production and Activates IRAK and NFκB

Douglas S. Robinson, Kazuko Shibuya, Alice Mui et al. · Immunity · 1997 · 723 citations · Full text

Cytokine, Immunodeficiencies, Immunology +11