Alzheimer's disease presenilin-1 exon 9 deletion and L250S mutations sensitiZe SH-SY5Y neuroblastoma cells to hyperosmotic stress-induced apoptosis

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

Tim R. Mosmann · Journal of Immunological Methods · 1983 · 55.6K citations

Life Sciences, Cell Biology, Apoptosis +14

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

A H Wyllie · Nature · 1980 · 4.5K citations

Life Sciences, Cell Biology, Molecular Biology +14

Secreted amyloid β–protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

Donalyn Scheuner, Christopher B. Eckman, M. Jensen et al. · Nature Medicine · 1996 · 2.6K citations

Life Sciences, Neurobiology, Neuroscience +16

Regulation of Neuronal Survival by the Serine-Threonine Protein Kinase Akt

Henryk Dudek, Sandeep Robert Datta, Thomas Franke et al. · Science · 1997 · 2.5K citations

Life Sciences, Neurobiology, Neuroscience +16

Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function

Maria Ankarcrona, Jeannette M. Dypbukt, Emanuela Bonfoco et al. · Neuron · 1995 · 1.9K citations · Full text

Life Sciences, Neurobiology, Neuroscience +14