Integrative metabolome and transcriptome profiling reveals discordant energetic stress between mouse strains with differential sensitivity to acrolein‐induced acute lung injury

James P. Fabisiak, Mario Medvedovic, Danny C. Alexander, Jonathan E. McDunn, Vincent J. Concel, Kiflai Bein, An‐Soo Jang, Annerose Berndt, Louis J. Vuga, Kelly A. Brant,

Molecular Nutrition & Food Research · 2011 · 31 citations · 48 references

Abstract

These findings suggest management of energetic stress varies between these strains, and that the ability to evoke auxiliary energy generating pathways rapidly and effectively may be critical in enhancing survival during acute lung injury in mice.

References

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