D. Grahame Hardie

Complexes between the LKB1 tumor suppressor, STRADα/β and MO25α/β are upstream kinases in the AMP-activated protein kinase cascade

Simon A. Hawley, Jérôme Boudeau, Jennifer L. Reid et al. · Journal of Biology · 2003 · 1.6K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Calmodulin-dependent protein kinase kinase-β is an alternative upstream kinase for AMP-activated protein kinase

Simon A. Hawley, David Pan, Kirsty J. Mustard et al. · Cell Metabolism · 2005 · 1.6K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +7

LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR‐1

José M. Lizcano, Olga Göransson, Rachel Toth et al. · The EMBO Journal · 2004 · 1.4K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +6

Characterization of the AMP-activated Protein Kinase Kinase from Rat Liver and Identification of Threonine 172 as the Major Site at Which It Phosphorylates AMP-activated Protein Kinase

Simon A. Hawley, Matt Davison, Angela Woods et al. · Journal of Biological Chemistry · 1996 · 1.3K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

AMP-Activated Protein Kinase in Metabolic Control and Insulin Signaling

Mhairi C. Towler, D. Grahame Hardie · Circulation Research · 2007 · 1.2K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17