Role of SIRT1 in homologous recombination

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

Konrad T. Howitz, Kevin J. Bitterman, Haim Cohen et al. · Nature · 2003 · 3.7K citations

Lifespan Extension, Natural Sciences, Molecular Biology +5

hSIR2SIRT1 Functions as an NAD-Dependent p53 Deacetylase

Homayoun Vaziri, Scott Dessain, Elinor Ng Eaton et al. · Cell · 2001 · 2.6K citations · Full text

Transcriptional Regulation, Hsir2sirt1 Functions, Molecular Biology +4

Negative Control of p53 by Sir2α Promotes Cell Survival under Stress

Jianyuan Luo, Anatoly Nikolaev, Shin‐ichiro Imai et al. · Cell · 2001 · 2.1K citations · Full text

Cell Regulation, Cell Signaling, Apoptosis +9

Requirement of NAD and <i>SIR2</i> for Life-Span Extension by Calorie Restriction in <i>Saccharomyces cerevisiae</i>

Su-Ju Lin, Pierre‐Antoine Defossez, Leonard Guarente · Science · 2000 · 1.8K citations

Anti-aging, Genetics, Molecular Biology +21

Pathways of DNA Double-Strand Break Repair during the Mammalian Cell Cycle

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