Synthesis of fused pyrido[2,3-d]pyrimidines by thermal isomerization of 4-amino-5-vinylpyrimidines

Both 2′,3′-dideoxythymidine and its 2′,3′-unsaturated derivative (2′,3′-dideoxythymidinene) are potent and selective inhibitors of human immunodeficiency virus replication in vitro

Masanori Baba, Rudi Pauwels, Piet Herdewijn et al. · Biochemical and Biophysical Research Communications · 1987 · 344 citations

Medicinal Chemistry, Medicine, Drug Discovery +9

EXPERIMENTAL AND CLINICAL USE OF FLUORINATED PYRIMIDINES IN CANCER CHEMOTHERAPY.

Charles Heidelberger, Fred J. Ansfield · PubMed · 1963 · 207 citations

Medicinal Chemistry, Advanced Cancer, Health Sciences +14

Potential of bromovinyldeoxyuridine in anticancer chemotherapy.

Erik De Clercq · PubMed · 1986 · 68 citations

Immunology, Pharmacotherapy, Period Bvu +17

Synchronous Six‐Electron Cyclization of Hexatriene Systems as a New Synthetic Principle for Preparation of Aromatic and Heteroaromatic Compounds

Christian Jutz, Rudolph M. Wagner · Angewandte Chemie International Edition in English · 1972 · 53 citations

Hexatriene Systems, Chemical Engineering, Engineering +7

Dye-sensitized photochemical autoxidation of aliphatic amines in nonaqueous media

Frederick Charles Schaefer, W. D. ZIMMERMANN · The Journal of Organic Chemistry · 1970 · 49 citations

Chemical Measurement, Engineering, Photochemistry +11