Concepedia

Phase II trial of dolastatin-10 in patients with advanced breast cancer

Edith A. Perez, David W. Hillman, Paul A. S. Fishkin, James E. Krook, Winston Tan, Phillip Kuriakose, Steven R. Alberts, Shaker R. Dakhil

Investigational New Drugs · 2005 · 99 citations · 17 references

DOI

Concepts

References

17

Cancer Statistics, 2005

Ahmedin Jemal, Thomas S. Murray, Elizabeth Ward et al. · CA A Cancer Journal for Clinicians · 2005 · 5.5K citations · Full text

, , +16

The isolation and structure of a remarkable marine animal antineoplastic constituent: dolastatin 10

George R. Pettit, Yoshiaki Kamano, Cherry L. Herald et al. · Journal of the American Chemical Society · 1987 · 573 citations

, , +14

Dolastatin 10, a powerful cytostatic peptide derived from a marine animal

Ruoli Bai, George R. Petit, Ernest Hamel · Biochemical Pharmacology · 1990 · 318 citations

, , +10

Binding of dolastatin 10 to tubulin at a distinct site for peptide antimitotic agents near the exchangeable nucleotide and vinca alkaloid sites.

R Bai, George R. Pettit, Ernest Hamel · Journal of Biological Chemistry · 1990 · 285 citations · Full text

, , +19

Antineoplastic agents. Part 189. The absolute configuration and synthesis of natural (-)-dolastatin 10

George R. Pettit, Sheo B. Singh, Fiona Hogan et al. · Journal of the American Chemical Society · 1989 · 178 citations

, , +14