Polymorphic metabolism of metoprolol: Clinical studies

POLYMORPHIC HYDROXYLATION OF DEBRISOQUINE IN MAN

A. Mahgoub, L. G. Dring, Jeffrey R. Idle et al. · The Lancet · 1977 · 1.2K citations

Bioorganic Chemistry, Biochemistry, Medicine +6

Adverse reactions to bendrofluazide and propranolol for the treatment of mild hypertension. Report of Medical Research Council Working Party on Mild to Moderate Hypertension.

Gerson Greenburg · PubMed · 1981 · 547 citations

MEDICAL NEMESIS

George Discombe · The Lancet · 1974 · 377 citations

Oxidation Phenotype — A Major Determinant of Metoprolol Metabolism and Response

M. S. Lennard, J H Silas, Stephen Freestone et al. · New England Journal of Medicine · 1982 · 278 citations

Lipid Peroxidation, Genetic Epidemiology, Human Polymorphism +25

Differential stereoselective metabolism of metoprolol in extensive and poor debrisoquin metabolizers

M. S. Lennard, Geoffrey T. Tucker, J H Silas et al. · Clinical Pharmacology & Therapeutics · 1983 · 211 citations

Metabolomic Profiling, Secondary Metabolite, Plasma Aucs +19