Concepedia

Absorption and chemopreventive targets of sulforaphane in humans following consumption of broccoli sprouts or a myrosinase-treated broccoli sprout extract

Lauren L. Atwell, Anna Hsu, Carmen P. Wong, Jan F. Stevens, Deborah Bella, Tianwei Yu, Clifford B. Pereira, Christiane V. Löhr, J. Mark Christensen, Roderick H. Dashwood,

Molecular Nutrition & Food Research · 2014 · 127 citations · 31 references

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Abstract

We conclude that the dietary form and dosing schedule of SFN may impact SFN absorption and efficacy in human trials.

References

31

A Novel Mechanism of Chemoprotection by Sulforaphane

Melinda C. Myzak, P. Andrew Karplus, Fung‐Lung Chung et al. · Cancer Research · 2004 · 492 citations

Chemoprotective glucosinolates and isothiocyanates of broccoli sprouts: metabolism and excretion in humans.

Theresa A. Shapiro, Jed W. Fahey, Kristina L. Wade et al. · PubMed · 2001 · 463 citations

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Human metabolism and excretion of cancer chemoprotective glucosinolates and isothiocyanates of cruciferous vegetables.

Theresa A. Shapiro, Jed W. Fahey, Kristina L. Wade et al. · PubMed · 1998 · 422 citations

, , +19

Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in <i>Apc</i> <sup>min</sup> mice

Melinda C. Myzak, Wan Mohaiza Dashwood, Gayle A. Orner et al. · The FASEB Journal · 2006 · 339 citations · Full text

Preclinical and clinical evaluation of sulforaphane for chemoprevention in the breast

Brian Cornblatt, Lingxiang Ye, Albena T. Dinkova‐Kostova et al. · Carcinogenesis · 2007 · 318 citations · Full text