Cell cycle-linked MeCP2 phosphorylation modulates adult neurogenesis involving the Notch signalling pathway

Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

Ruthie E. Amir, Ignatia B. Van den Veyver, Mimi Wan et al. · Nature Genetics · 1999 · 5K citations

Chromatin, Genome Instability, Transcriptional Regulation +11

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

Peter Lloyd Jones, Gert Jan C. Veenstra, Paul A. Wade et al. · Nature Genetics · 1998 · 2.7K citations

Histone Modifications, Chromatin, Transcriptional Regulation +14

Derepression of BDNF Transcription Involves Calcium-Dependent Phosphorylation of MeCP2

Wen Chen, Qiang Chang, Yingxi Lin et al. · Science · 2003 · 1.2K citations

A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

James R. Bischoff · The EMBO Journal · 1998 · 1.2K citations · Full text

Medicine, Drosophila Aurora Kinase, Colorectal Cancer +7

Brain-Specific Phosphorylation of MeCP2 Regulates Activity-Dependent Bdnf Transcription, Dendritic Growth, and Spine Maturation

Zhaolan Zhou, Elizabeth J. Hong, Sonia Cohen et al. · Neuron · 2006 · 852 citations · Full text

Synaptic Plasticity, Neuroregeneration, Molecular Neuroscience +10