Effect of organic acids, trypsin inhibitors and dietary protein on the pharmacological activity of recombinant human granulocyte colony-stimulating factor (rhG-CSF) in rats

Recombinant Human Granulocyte Colony-Stimulating Factor: Effects on Normal and Leukemic Myeloid Cells

L M Souza, Thomas C. Boone, Janice Gabrilove et al. · Science · 1986 · 1.2K citations

Life Sciences, Hematology, Molecular Biology +14

Molecular cloning and expression of cDNA for human granulocyte colony-stimulating factor

Shigekazu Nagata, Masayuki Tsuchiya, Shigetaka Asano et al. · Nature · 1986 · 825 citations

Life Sciences, Immunology, Molecular Biology +5

Phase I/II study of recombinant human granulocyte colony-stimulating factor in patients receiving intensive chemotherapy for small cell lung cancer

MH Bronchud, J.H. Scarffe, Nicholas Thatcher et al. · British Journal of Cancer · 1987 · 597 citations · Full text

Medicine, Hematology, Oncology +15

Feedback Regulation of Pancreatic Enzyme Secretion as a Mechanism for Trypsin Inhibitor-Induced Hypersecretion in Rats

G. M. Green, R. Lee Lyman · Experimental Biology and Medicine · 1972 · 453 citations

Life Sciences, Animal Sciences, Biochemistry +17

Crystal structure of the complex of porcine trypsin with soybean trypsin inhibitor (Kunitz) at 2.6 Å resolution

Robert M. Sweet, H.T. Wright, J. Janin et al. · Biochemistry · 1974 · 433 citations

Life Sciences, Biochemistry, Biophysics +10