Concepedia

Conversion From Twice-Daily to Once-Daily Tacrolimus Does Not Reduce Intrapatient Variability in Tacrolimus Exposure

Nauras Shuker, M. Cadogan, Teun van Gelder, Joke I. Roodnat, Marcia M. L. Kho, Willem Weimar, Dennis A. Hesselink

Therapeutic Drug Monitoring · 2014 · 30 citations · 17 references

DOI

Abstract

Although conversion from Tac-TD to Tac-OD significantly reduces tacrolimus exposure as measured by C0 and seems safe, it does not reduce IPV in tacrolimus exposure.

References

17

Rates and Risk Factors for Nonadherence to the Medical Regimen After Adult Solid Organ Transplantation

Mary Amanda Dew, Andrea F. DiMartini, Annette De Vito Dabbs et al. · Transplantation · 2007 · 564 citations

THE EFFECT OF REGRESSION TO THE MEAN IN EPIDEMIOLOGIC AND CLINICAL STUDIES

C.E. Davis · American Journal of Epidemiology · 1976 · 392 citations

High within-patient variability in the clearance of tacrolimus is a risk factor for poor long-term outcome after kidney transplantation

Lennaert C. P. Borra, Joke I. Roodnat, J. Kal et al. · Nephrology Dialysis Transplantation · 2010 · 237 citations · Full text

Improved Adherence to Tacrolimus Once-Daily Formulation in Renal Recipients

Dirk Kuypers, Patrick Peeters, Jacques Sennesael et al. · Transplantation · 2012 · 224 citations · Full text

Conversion of Stable Kidney Transplant Recipients From a Twice Daily Prograf-Based Regimen to a Once Daily Modified Release Tacrolimus-Based Regimen

Rita R. Alloway, S. Steinberg, Khalid Khalil et al. · Transplantation Proceedings · 2005 · 161 citations

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