Dennis A. Hesselink

Duration and key determinants of infectious virus shedding in hospitalized patients with coronavirus disease-2019 (COVID-19)

Jeroen J. A. van Kampen, David van de Vijver, Pieter L. A. Fraaij et al. · Nature Communications · 2021 · 843 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +14

Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimus

Dennis A. Hesselink · Clinical Pharmacology & Therapeutics · 2003 · 653 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Cyclosporine Interacts with Mycophenolic Acid by Inhibiting the Multidrug Resistance-Associated Protein 2

Dennis A. Hesselink, Reinier M. van Hest, Ron A. A. Mathôt et al. · American Journal of Transplantation · 2005 · 297 citations

Veterinary Medicine, Pharmacology, Pharmacotherapy +14

Shedding of infectious virus in hospitalized patients with coronavirus disease-2019 (COVID-19): duration and key determinants

Jeroen J. A. van Kampen, David van de Vijver, Pieter L. A. Fraaij et al. · medRxiv · 2020 · 255 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +16

A New Functional CYP3A4 Intron 6 Polymorphism Significantly Affects Tacrolimus Pharmacokinetics in Kidney Transplant Recipients

Laure Elens, Rachida Bouamar, Dennis A. Hesselink et al. · Clinical Chemistry · 2011 · 240 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17