Conversion From Calcineurin Inhibitor to Mycophenolate Mofetil-Based Immunosuppression Changes the Frequency and Phenotype of CD4+FOXP3+ Regulatory T Cells - Concepedia

Concepedia

Publication | Closed Access

Conversion From Calcineurin Inhibitor to Mycophenolate Mofetil-Based Immunosuppression Changes the Frequency and Phenotype of CD4+FOXP3+ Regulatory T Cells

84

Citations

21

References

2009

Year

Ahmet Demirkıran, Varsha D. K. D. Sewgobind, Joyce van der Weijde, Alice Kok, Carla C. Baan, Jaap Kwekkeboom, Hugo W. Tilanus, Herold J. Metselaar, Luc J. W. van der Laan

Transplantation

Abstract

Conversion to MMF increases the percentage and CD25 expression of CD4+FOXP3+ cells indicating that MMF therapy can overturn the repressive effect of CNI on circulating Treg levels and therefore may promote Treg-mediated suppression of alloreactivity.

References

	Year	Citations

Page 1