Synthesis and analysis of conjugates of the major vitamin E metabolite, α-CEHC

Is vitamin E the only lipid-soluble, chain-breaking antioxidant in human blood plasma and erythrocyte membranes?

Graham W. Burton, Anne Joyce, K. U. Ingold · Archives of Biochemistry and Biophysics · 1983 · 806 citations

Life Sciences, Biochemistry, Nutritional Sciences +17

d-alpha-tocopherol inhibition of vascular smooth muscle cell proliferation occurs at physiological concentrations, correlates with protein kinase C inhibition, and is independent of its antioxidant properties.

Andrea Tasinato, Daniel Boscoboinik, Gianna Bartoli et al. · Proceedings of the National Academy of Sciences · 1995 · 286 citations · Full text

Life Sciences, Biochemistry, Cell Biology +10

α-Tocopherol specifically inactivates cellular protein kinase C α by changing its phosphorylation state

Roberta Ricciarelli, Andrea Tasinato, Sophie Clément et al. · Biochemical Journal · 1998 · 263 citations · Full text

Life Sciences, Biochemistry, Cell Biology +13

Novel urinary metabolite of alpha-tocopherol, 2,5,7,8-tetramethyl-2(2’-carboxyethyl)-6-hydroxychroman, as an indicator of an adequate vitamin E supply?

M. Schultz, Marcel Leist, M. Petrzika et al. · American Journal of Clinical Nutrition · 1995 · 243 citations

Life Sciences, Nutrition, Nutritional Sciences +15

Urinary excretion of 2,7,8-trimethyl-2-(β-carboxyethyl)-6-hydroxychroman is a major route of elimination of γ-tocopherol in humans

Joy E. Swanson, Robert N. Ben, Graham W. Burton et al. · Journal of Lipid Research · 1999 · 194 citations · Full text

Agriculture, Nutrition, Nutritional Sciences +12