A non-proteolytic role for ubiquitin in Tat-mediated transactivation of the HIV-1 promoter

Mdm2 promotes the rapid degradation of p53

Ygal Haupt, Ruth Maya, Anat Kazaz et al. · Nature · 1997 · 4.5K citations

Tumor Biology, Medicine, Rapid Degradation +6

Degradation of CFTR by the ubiquitin-proteasome pathway

Cristina L. Ward, Satoshi ŌMURA, Ron R. Kopito · Cell · 1995 · 1.3K citations · Full text

A Novel CDK9-Associated C-Type Cyclin Interacts Directly with HIV-1 Tat and Mediates Its High-Affinity, Loop-Specific Binding to TAR RNA

Ping Wei, Mitchell Garber, Shi-Min Fang et al. · Cell · 1998 · 1.2K citations · Full text

Tar Rna, Signal Transduction, Human Retrovirus +8

The SCFbeta -TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in Ikappa Balpha and beta -catenin and stimulates Ikappa Balpha ubiquitination in vitro

Jeffrey Winston, Peter R. Strack, Peggy Beer‐Romero et al. · Genes & Development · 1999 · 941 citations · Full text

Ubiquitin-dependent c-Jun degradation in vivo is mediated by the δ domain

Mathias Treier, Lena Staszewski, Dirk Bohmann · Cell · 1994 · 927 citations

Signal Transduction, Cell Regulation, Molecular Regulation +10