Mll2 Controls Cardiac Lineage Differentiation of Mouse Embryonic Stem Cells by Promoting H3K4me3 Deposition at Cardiac-Specific Genes

The mutational landscape of lethal castration-resistant prostate cancer

Catherine S. Grasso, Yi-Mi Wu, Dan R. Robinson et al. · Nature · 2012 · 2.6K citations

Urology, Somatic Variant, Genitourinary Cancer +2

Initial genome sequencing and analysis of multiple myeloma

Michael A. Chapman, Michael S. Lawrence, Jonathan J. Keats et al. · Nature · 2011 · 1.4K citations · Full text

Exome sequencing identifies MLL2 mutations as a cause of Kabuki syndrome

Sarah Ng, Abigail W. Bigham, Kati J. Buckingham et al. · Nature Genetics · 2010 · 1.3K citations · Full text

Engineering, Mendelian Disorder, Identifies Mll2 Mutations +9

UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development

Karl Agger, Paul A. Cloos, Jesper Frank Christensen et al. · Nature · 2007 · 1.3K citations

Histone Modifications, Chromatin, Histone H3k27 +11

Analysis of the coding genome of diffuse large B-cell lymphoma

Laura Pasqualucci, Giulia Fabbri, Jing Ma et al. · Nature Genetics · 2011 · 957 citations · Full text

Hematological Malignancy, Lymphoid Neoplasia, Next-generation Sequencing +7