UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development

Karl Agger, Paul A. Cloos, Jesper Frank Christensen, +7

Nature

Histone ModificationsChromatinHistone H3k27Chromatin RemodelingEpigenetic Change +9

The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3

Paul A. Cloos, Karl Agger, Alessio Maiolica, +4

Nature

Histone ModificationsChromatinHistone H3BiochemistryChromatin Remodeling +9

RBP2 Belongs to a Family of Demethylases, Specific for Tri-and Dimethylated Lysine 4 on Histone 3

Jesper Frank Christensen, Karl Agger, Paul A. Cloos, +7

Cell

Histone ModificationsChromatinBiochemistryRbp2 BelongsNatural Sciences +6

The H3K27me3 demethylase JMJD3 contributes to the activation of the<i>INK4A–ARF</i>locus in response to oncogene- and stress-induced senescence

Karl Agger, Paul A. Cloos, Lise Rudkjær, +2

Genes & Development

Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2

Diego Pasini, Klaus Hansen, Jesper Frank Christensen, +3

Genes & Development

Histone ModificationsEpigenetic ChangePrc2 ComplexMolecular BiologyGene Regulatory Network +20

Jarid2 binds mono-ubiquitylated H2A lysine 119 to mediate crosstalk between Polycomb complexes PRC1 and PRC2

Sarah Cooper, Anne Grijzenhout, E. Underwood, +10

Nature Communications

A Novel Repressive E2F6 Complex Containing the Polycomb Group Protein, EPC1, That Interacts with EZH2 in a Proliferation-specific Manner

Claire Attwooll, Sergio Oddi, Elena Prosperini, +6

Journal of Biological Chemistry

Continual removal of H3K9 promoter methylation by Jmjd2 demethylases is vital for <scp>ESC</scp> self‐renewal and early development

Marianne Terndrup Pedersen, Susanne M. Kooistra, Aliaksandra Radzisheuskaya, +6

The EMBO Journal

Epigenetic ChangeGeneticsDna MethylationMolecular BiologyEpigenetics +15

Jmjd2/Kdm4 demethylases are required for expression of<i>Il3ra</i>and survival of acute myeloid leukemia cells

Karl Agger, Satoru Miyagi, Marianne Terndrup Pedersen, +3

Genes & Development

Mixed-phenotype Acute LeukemiaImmunologyTumor BiologyMyeloid NeoplasiaHematological Malignancy +16

The Demethylase JMJD2C Localizes to H3K4me3-Positive Transcription Start Sites and Is Dispensable for Embryonic Development

Marianne Terndrup Pedersen, Karl Agger, Anne Laugesen, +4

Molecular and Cellular Biology