Analysis of the coding genome of diffuse large B-cell lymphoma

Laura Pasqualucci, Giulia Fabbri, Jing Ma, +13

Nature Genetics

Hematological MalignancyLymphoid NeoplasiaNext-generation SequencingPathologyMolecular Genetics +5

Inactivating mutations of acetyltransferase genes in B-cell lymphoma

Laura Pasqualucci, David Dominguez-Sola, Annalisa Chiarenza, +15

Nature

B-cell LymphomaLymphoid NeoplasiaPathologyAdult T-cell Leukemia-lymphomaMedicine +2

Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities

Carl M. Gay, C. Allison Stewart, Elizabeth M. Park, +27

Cancer Cell

ImmunogeneticsSystems BiologyDistinct Therapeutic VulnerabilitiesAutoimmune DiseaseTranscription Factor Programs +9

Analysis of the chronic lymphocytic leukemia coding genome: role of <i>NOTCH1</i> mutational activation

Giulia Fabbri, Silvia Rasi, Davide Rossi, +24

The Journal of Experimental Medicine

Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia

Davide Rossi, Silvia Rasi, Giulia Fabbri, +21

Blood

Genome-wide Mapping and Characterization of Notch-Regulated Long Noncoding RNAs in Acute Leukemia

Thomas Trimarchi, Erhan Bilal, Panagiotis Ntziachristos, +4

Cell

Hematological MalignancyChromatinTranscriptional RegulationFunctional GenomicsMedicine +9

The coding genome of splenic marginal zone lymphoma: activation of <i>NOTCH2</i> and other pathways regulating marginal zone development

Davide Rossi, Marco Fangazio, Alessio Bruscaggin, +36

The Journal of Experimental Medicine

Lymphocyte DevelopmentImmunologyPathologyB Cell DevelopmentMarginal Zone Development +15

Genetic lesions associated with chronic lymphocytic leukemia transformation to Richter syndrome

Giulia Fabbri, Hossein Khiabanian, Antony B. Holmes, +6

The Journal of Experimental Medicine

Mixed-phenotype Acute LeukemiaPathologyRs LesionsTumor BiologyHematological Malignancy +16

Disruption of BIRC3 associates with fludarabine chemorefractoriness in TP53 wild-type chronic lymphocytic leukemia

Davide Rossi, Marco Fangazio, Silvia Rasi, +22

Blood

Common nonmutational<i>NOTCH1</i>activation in chronic lymphocytic leukemia

Giulia Fabbri, Antony B. Holmes, Mara Viganotti, +10

Proceedings of the National Academy of Sciences