Concepedia

Concentration-dependent control of pyruvate kinase M mutually exclusive splicing by hnRNP proteins

Mo Chen, Charles J. David, James L. Manley

Nature Structural & Molecular Biology · 2012 · 158 citations · 32 references

DOI

Concepts

References

32

On the Origin of Cancer Cells

Otto Warbürg · Science · 1956 · 13.3K citations

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Alternative isoform regulation in human tissue transcriptomes

Eric T. Wang, Rickard Sandberg, Shujun Luo et al. · Nature · 2008 · 5.4K citations · Full text

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Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing

Qun Pan, Ofer Shai, Leo J. Lee et al. · Nature Genetics · 2008 · 4K citations

, , +16

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

Heather R. Christofk, Matthew G. Vander Heiden, Marian H. Harris et al. · Nature · 2008 · 2.8K citations

, , +16

The MicroRNA miR-124 Promotes Neuronal Differentiation by Triggering Brain-Specific Alternative Pre-mRNA Splicing

Eugene V. Makeyev, Jiangwen Zhang, Mónica A. Carrasco et al. · Molecular Cell · 2007 · 1.4K citations · Full text

, , +14