Concepedia

Splicing Fidelity

Splicing Fidelity is a molecular biology metric that quantifies the accuracy with which spliceosomal machinery discriminates canonical splice sites from cryptic or non-canonical sites during pre-mRNA processing to ensure correct intron excision and exon ligation.

71

Publications

4.8K

Citations

269

Authors

102

Institutions

Publications per year

2017–2026

15

Parents

Publications

71

iCLIP Predicts the Dual Splicing Effects of TIA-RNA Interactions

Zhen Wang, Melis Kayikci, Michael Briese et al. · PLoS Biology · 2010 · 257 citations · Full text

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Cryptic branch point activation allows accurate in vitro splicing of human β-globin intron mutants

Barbara Ruskin, J. M. Greene, Michael R. Green · Cell · 1985 · 239 citations

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Enhancement of foreign gene expression by a dicot intron in rice but not in tobacco is correlated with an increased level of mRNA and an efficient splicing of the intron

Akira Tanaka, Satoru Mita, Shozo Ohta et al. · Nucleic Acids Research · 1990 · 185 citations · Full text

, , +13

A putative ATP binding protein influences the fidelity of branchpoint recognition in yeast splicing

Sean M. Burgess, Joseph Couto, Christine Guthrie · Cell · 1990 · 182 citations

, , +13

Design of a Split Intein with Exceptional Protein Splicing Activity

Adam J. Stevens, Zachary Z. Brown, Neel H. Shah et al. · Journal of the American Chemical Society · 2016 · 179 citations · Full text

, , +13

1–5 of 71

Authors

269

  1. CG
    Christine Guthrie

    University of California, San Francisco, United States

    5 publications · 509 citations

    5

    h-index

  2. RK
    Ryszard Kole

    University of North Carolina at Chapel Hill, United States

    3 publications · 133 citations

    3

    h-index

  3. CB
    Christopher B. Burge

    Massachusetts Institute of Technology, United States

    2 publications · 92 citations

    2

    h-index

  4. IC
    Ian C. Eperon

    University of Leicester, United Kingdom

    2 publications · 60 citations

    2

    h-index

  5. AR
    Adrian R. Krainer

    Cold Spring Harbor Laboratory, United States

    2 publications · 72 citations

    2

    h-index

1–5 of 269

Institutions

102

  1. University of California, San Francisco

    San Francisco, United States

    7 h-index

    22 publications

    1.6K citations

  2. Johns Hopkins Medicine

    Baltimore, United States

    3 h-index

    10 publications

    1K citations

  3. Columbia University

    New York, United States

    3 h-index

    7 publications

    500 citations

  4. Memorial Sloan Kettering Cancer Center

    New York, United States

    3 h-index

    5 publications

    392 citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    3 h-index

    6 publications

    413 citations

  6. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    3 h-index

    8 publications

    360 citations

  7. Harvard University

    Cambridge, United States

    3 h-index

    15 publications

    951 citations

  8. Johns Hopkins University

    Baltimore, United States

    3 h-index

    10 publications

    1K citations

1–8 of 102

Venues

  1. Nucleic Acids Research

    7 publications · 327 citations

    7

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 7 publications · 310 citations

    7

    h-index

  3. Journal of Biological Chemistry

    JBC · 5 publications · 268 citations

    5

    h-index

  4. Nature Structural & Molecular Biology

    4 publications · 351 citations

    4

    h-index

  5. Molecular and Cellular Biology

    MCB · 4 publications · 129 citations

    4

    h-index

1–5