Characterizing the RNA targets and position-dependent splicing regulation by TDP-43

James Tollervey, Tomaž Curk, Boris Rogelj, +13

Nature Neuroscience

Transcriptional RegulationNatural SciencesGeneticsRna Binding ProteinsRna Splicing +8

iCLIP Predicts the Dual Splicing Effects of TIA-RNA Interactions

Zhen Wang, Melis Kayikci, Michael Briese, +6

PLoS Biology

Rna ProcessingTranscriptional RegulationExon InclusionNatural SciencesGenetics +11

Recursive splicing in long vertebrate genes

Christopher R. Sibley, Warren Emmett, Lorea Blázquez, +12

Nature

BiologyTranscriptional RegulationGeneticsRna SplicingGene Structure +6

CELF4 Regulates Translation and Local Abundance of a Vast Set of mRNAs, Including Genes Associated with Regulation of Synaptic Function

Jacy L. Wagnon, Michael Briese, Wenzhi Sun, +5

PLoS Genetics

Whole transcriptome profiling reveals the RNA content of motor axons

Michael Briese, Lena Saal, Silke Appenzeller, +3

Nucleic Acids Research

GeneticsWhole Transcriptome ProfilingTotal RnaTranscriptomics TechnologySocial Sciences +16

Deletion of smn-1, the Caenorhabditis elegans ortholog of the spinal muscular atrophy gene, results in locomotor dysfunction and reduced lifespan

Michael Briese, Behrooz Esmaeili, Sandrine Fraboulet, +5

Human Molecular Genetics

Neurodegenerative DiseasesCell LineageMolecular NeuroscienceDevelopmental BiologyDevelopmental Genetics +10

Subcellular transcriptome alterations in a cell culture model of spinal muscular atrophy point to widespread defects in axonal growth and presynaptic differentiation

Lena Saal, Michael Briese, Susanne Kneitz, +2

RNA

Cellular NeurobiologyCell SpecializationCellular PhysiologySocial SciencesTranscriptional Regulation +16

CLIP: Construction of cDNA libraries for high-throughput sequencing from RNAs cross-linked to proteins in vivo

Zhen Wang, James Tollervey, Michael Briese, +2

Methods

Rna ProcessingNatural SciencesGeneticsRna BiologyMolecular Biology +7

Loss of Tdp-43 disrupts the axonal transcriptome of motoneurons accompanied by impaired axonal translation and mitochondria function

Michael Briese, Lena Saal-Bauernschubert, Patrick Lüningschrör, +7

Acta Neuropathologica Communications

hnRNP R and its main interactor, the noncoding RNA 7SK, coregulate the axonal transcriptome of motoneurons

Michael Briese, Lena Saal-Bauernschubert, Changhe Ji, +6

Proceedings of the National Academy of Sciences