Novel bicyclic lactam inhibitors of thrombin: highly potent and selective inhibitors

Dibasic (Amidinoaryl)propanoic Acid Derivatives as Novel Blood Coagulation Factor Xa Inhibitors

Takayasu Nagahara, Yukio Yokoyama, Kazue Inamura et al. · Journal of Medicinal Chemistry · 1994 · 178 citations · Full text

Factor X, Medicinal Chemistry, Pharmaceutical Chemistry +15

A Versatile Synthesis of Amidines from Nitriles<i>Via</i>Amidoximes

Brian D. Judkins, D. G. Allen, Tracey A. Cook et al. · Synthetic Communications · 1996 · 103 citations

Engineering, Versatile Synthesis, Intermediate Benzamidoximes +7

BCH-2763, a Novel Potent Parenteral Thrombin Inhibitor, Is an Effective Antithrombotic Agent in Rodent Models of Arterial and Venous Thrombosis – Comparisons with Heparin, r-Hirudin, Hirulog, Inogatran and Argatroban

C D Finkle, Lorraine Leblond, Isabelle Deschênes et al. · Thrombosis and Haemostasis · 1998 · 43 citations

Thrombin Inhibitors, Immunology, Pharmacotherapy +17

Convenient One-Pot Synthesis of Sulfonyl Chlorides from Thiols Using Sulfuryl Chloride and Metal Nitrate

Young Jun Park, Hyun Ho Shin, Yong Hae Kim · Chemistry Letters · 1992 · 39 citations

Aryl Thiols, Chemical Engineering, Sulfonyl Chlorides +11

Synthesis of 2-amino-L-histidine(11) and 2-aminohistamine(12)

W. NAGAI, Kenneth L. Kirk, Louis A. Cohen · The Journal of Organic Chemistry · 1973 · 31 citations

Kenneth L. Kirk, Molecular Sciences, Bioorganic Chemistry +14