siRNA Silencing of the Mutant Keratin 12 Allele in Corneal Limbal Epithelial Cells Grown From Patients With Meesmann's Epithelial Corneal Dystrophy - Concepedia

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Publication | Open Access

siRNA Silencing of the Mutant Keratin 12 Allele in Corneal Limbal Epithelial Cells Grown From Patients With Meesmann's Epithelial Corneal Dystrophy

DOI Full Paper Access

36

Citations

32

References

2014

Year

David Courtney, Sarah D. Atkinson, Edwin H. A. Allen, Jonathan E. Moore, Colum P. Walsh, Deena M. Leslie Pedrioli, C J MacEwen, Graziella Pellegrini, Eleonora Maurizi, Chiara Serafini,

Investigative Ophthalmology & Visual Science

Abstract

Combined with an effective delivery vehicle this siRNA approach represents a viable treatment option for prevention of the MECD pathology observed in K12-Leu132Pro heterozygous individuals.

References

	Year	Citations

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