Eleonora Maurizi

CRISPR/Cas9 DNA cleavage at SNP-derived PAM enables both in vitro and in vivo KRT12 mutation-specific targeting

David Courtney, Jonathan E. Moore, Sarah D. Atkinson et al. · Gene Therapy · 2015 · 125 citations · Full text

Effective In Vivo Topical Delivery of siRNA and Gene Silencing in Intact Corneal Epithelium Using a Modified Cell-Penetrating Peptide

Davide Schiroli, María J. Gómara, Eleonora Maurizi et al. · Molecular Therapy — Nucleic Acids · 2019 · 41 citations · Full text

Nanomedicine, Engineering, Ophthalmology +9

Development of Allele-Specific Gene-Silencing siRNAs for TGFBI Arg124Cys in Lattice Corneal Dystrophy Type I

David Courtney, Sarah D. Atkinson, Jonathan E. Moore et al. · Investigative Ophthalmology & Visual Science · 2014 · 40 citations · Full text

Protein Composition of TGFBI-R124C- and TGFBI-R555W- Associated Aggregates Suggests Multiple Mechanisms Leading to Lattice and Granular Corneal Dystrophy

David Courtney, Ebbe Toftgaard Poulsen, Susan Kennedy et al. · Investigative Ophthalmology & Visual Science · 2015 · 39 citations · Full text

siRNA Silencing of the Mutant Keratin 12 Allele in Corneal Limbal Epithelial Cells Grown From Patients With Meesmann's Epithelial Corneal Dystrophy

David Courtney, Sarah D. Atkinson, Edwin H. A. Allen et al. · Investigative Ophthalmology & Visual Science · 2014 · 36 citations · Full text