Concepedia

Design, synthesis and biological evaluation of new thalidomide analogues as TNF-α and IL-6 production inhibitors

Charlotte Chaulet, Cécile Croix, David Alagille, Sylvain Normand, Adriana Delwail, Laure Favot, Jean‐Claude Lecron, Marie‐Claude Viaud‐Massuard

Bioorganic & Medicinal Chemistry Letters · 2010 · 48 citations · 10 references

DOI

Concepts

References

10

Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes.

E P Sampaio, Euzenir Nunes Sarno, Ruth Galilly et al. · The Journal of Experimental Medicine · 1991 · 1.2K citations · Full text

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THALIDOMIDE AND CONGENITAL ABNORMALITIES

W. G. McBride · The Lancet · 1961 · 1.1K citations

, , +16

Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation.

André L. Moreira, E P Sampaio, A Zmuidzinas et al. · The Journal of Experimental Medicine · 1993 · 1.1K citations · Full text

, , +14

THALIDOMIDE AND CONGENITAL ABNORMALITIES

W. Lenz, RudolfA. Pfeiffer, W Kosenow et al. · The Lancet · 1962 · 376 citations

, , +16

Amino-substituted thalidomide analogs: Potent inhibitors of TNF-α production

George W. Muller, Roger Chen, Shaei‐Yun Huang et al. · Bioorganic & Medicinal Chemistry Letters · 1999 · 339 citations

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