Amino-substituted thalidomide analogs: Potent inhibitors of TNF-α production

Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes.

E P Sampaio, Euzenir Nunes Sarno, Ruth Galilly et al. · The Journal of Experimental Medicine · 1991 · 1.2K citations · Full text

Medicine, Immunology, Pharmacology +14

Treatment of Crohn's disease with anti-tumor necrosis factor chimeric monoclonal antibody (cA2)

Hendrik M. van Dullemen, Sander J. H. van Deventer, Daan W. Hommes et al. · Gastroenterology · 1995 · 1.1K citations

Pharmacy, Immunology, Immunotherapy +9

Thalidomide in the treatment of lepra reactions

J Sheskin · Clinical Pharmacology & Therapeutics · 1965 · 533 citations

Medicine, Dermatology, Infectious Diseases +7

Structural Modifications of Thalidomide Produce Analogs with Enhanced Tumor Necrosis Factor Inhibitory Activity

George W. Muller, Laura G. Corral, Mary G. Shire et al. · Journal of Medicinal Chemistry · 1996 · 157 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9

Thalidomide as Treatment of Refractory Aphthous Ulceration Related to Human Immunodeficiency Virus Infection

David L. Paterson, Paul R. Georghiou, Anthony Allworth et al. · Clinical Infectious Diseases · 1995 · 103 citations

Pharmacy, Infectious Diseases, Pharmacotherapy +8