Concepedia

Interaction of Akt-Phosphorylated Ataxin-1 with 14-3-3 Mediates Neurodegeneration in Spinocerebellar Ataxia Type 1

Hung-Kai Chen, Pedro Fernández-Fúnez, Summer F. Acevedo, Yung C. Lam, Michael D. Kaytor, Michael Fernández, Alastair Aitken, Efthimios M. C. Skoulakis, Harry T. Orr, Juan Botas,

Cell · 2003 · 413 citations · 24 references

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24

Neurodegenerative Tauopathies

Virginia M.‐Y. Lee, Michel Goedert, John Q. Trojanowski · Annual Review of Neuroscience · 2001 · 2.4K citations

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Decreased nuclear β‐catenin, tau hyperphosphorylation and neurodegeneration in GSK‐3β conditional transgenic mice

José J. Lucas · The EMBO Journal · 2001 · 898 citations · Full text

, , +13

Dopamine-dependent neurotoxicity of α-synuclein: A mechanism for selective neurodegeneration in Parkinson disease

Jin Xu, Shyan‐Yuan Kao, Frank J.S. Lee et al. · Nature Medicine · 2002 · 768 citations

, , +16

Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1

Christopher J. Cummings, Michael A. Mancini, Barbara Antalffy et al. · Nature Genetics · 1998 · 743 citations

, , +14

Identification of genes that modify ataxin-1-induced neurodegeneration

Pedro Fernández-Fúnez, María Laura Niño-Rosales, Béatrice Gouyon et al. · Nature · 2000 · 662 citations

, , +12