Bisphosphonates to Prevent Skeletal Morbidity in Patients with Lung Cancer with Bone Metastases

A Randomized, Placebo-Controlled Trial of Zoledronic Acid in Patients With Hormone-Refractory Metastatic Prostate Carcinoma

Fred Saad, Donald M. Gleason, Robin Murray et al. · JNCI Journal of the National Cancer Institute · 2002 · 1.7K citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

Structure-Activity Relationships for Inhibition of Farnesyl Diphosphate Synthase in Vitro and Inhibition of Bone Resorption in Vivo by Nitrogen-Containing Bisphosphonates

James E. Dunford, Keith Thompson, Fraser P. Coxon et al. · Journal of Pharmacology and Experimental Therapeutics · 2001 · 896 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Long‐term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma

Lee S. Rosen, David Gordon, Mary Kaminski et al. · Cancer · 2003 · 875 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +10

Novel Antiangiogenic Effects of the Bisphosphonate Compound Zoledronic Acid

Jeanette M. Wood, Karine Bonjean, Stephan Ruetz et al. · Journal of Pharmacology and Experimental Therapeutics · 2002 · 851 citations

Medicine, Medicinal Chemistry, Pharmacology +16

Zoledronic Acid Versus Placebo in the Treatment of Skeletal Metastases in Patients With Lung Cancer and Other Solid Tumors: A Phase III, Double-Blind, Randomized Trial—The Zoledronic Acid Lung Cancer and Other Solid Tumors Study Group

Lee S. Rosen, David Gordon, Simon Tchekmedyian et al. · Journal of Clinical Oncology · 2003 · 727 citations

Medicine, Oncology, Pharmacotherapy +17