Methyltransferases mediate cell memory of a genotoxic insult

DNA Methyltransferases Dnmt3a and Dnmt3b Are Essential for De Novo Methylation and Mammalian Development

Masaki Okano, Daphne W. Bell, Daniel A. Haber et al. · Cell · 1999 · 6K citations · Full text

Histone Modifications, Chromatin, Dna Methyltransferases Dnmt3a +13

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

En Li, Timothy H. Bestor, Rudolf Jaenisch · Cell · 1992 · 3.9K citations

Developmental Biology, Embryonic Lethality, Epigenetic Change +8

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion

Françis Rodier, Jean‐Philippe Coppé, Christopher K. Patil et al. · Nature Cell Biology · 2009 · 2.1K citations · Full text

Inflammation, Dna Damage, Aging +8

The comet assay: a method to measure DNA damage in individual cells

Peggy L. Olive, Judit P. Banáth · Nature Protocols · 2006 · 1.8K citations

Chromatin, Genome Instability, Comet Assay +12

Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons

Jian Feng, Yu Zhou, Susan L. Campbell et al. · Nature Neuroscience · 2010 · 1K citations · Full text

Chromatin, Synaptic Plasticity, Molecular Neuroscience +11