Concepedia

Thrombopoietin (TPO) induces c-myc expression through a PI3K- and MAPK-dependent pathway that is not mediated by Akt, PKCζ or mTOR in TPO-dependent cell lines and primary megakaryocytes

Supantitra Chanprasert, Amy E. Geddis, Charlene F. Barroga, Norma E. Fox, Kenneth Kaushansky

Cellular Signalling · 2005 · 40 citations · 52 references

DOI

Concepts

References

52

Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

Sandeep Robert Datta, Henryk Dudek, Xu Tao et al. · Cell · 1997 · 5.7K citations · Full text

, , +16

Induction of apoptosis in fibroblasts by c-myc protein

Gérard I. Evan, Andrew H. Wyllie, Christopher S. Gilbert et al. · Cell · 1992 · 3K citations

, , +12

Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand

Frédéric J. de Sauvage, Philip E. Hass, Susan D. Spencer et al. · Nature · 1994 · 1.3K citations

, , +11

Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo

Si Lok, Kenneth Kaushansky, Richard D. Holly et al. · Nature · 1994 · 1.1K citations

, , +9

Protein Kinase C Isotypes Controlled by Phosphoinositide 3-Kinase Through the Protein Kinase PDK1

J. Ann Le Good, Wolfgang Ziegler, Davey B. Parekh et al. · Science · 1998 · 1.1K citations

, , +15