Susan D. Spencer

Targeting HER2-Positive Breast Cancer with Trastuzumab-DM1, an Antibody–Cytotoxic Drug Conjugate

Gail D. Lewis Phillips, Guangmin Li, Debra L. Dugger et al. · Cancer Research · 2008 · 1.6K citations

Drug Targeting, Breast Oncology, Disulfide Linkers +12

Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index

Jagath R. Junutula, Helga Raab, Suzanna Clark et al. · Nature Biotechnology · 2008 · 1.3K citations

Medicinal Chemistry, Immunocytochemical Technique, Drug Targeting +10

Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand

Frédéric J. de Sauvage, Philip E. Hass, Susan D. Spencer et al. · Nature · 1994 · 1.3K citations

Inflammation, Thrombosis, Thrombopoiesis +9

Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons

Craig Crowley, Susan D. Spencer, Merry Nishimura et al. · Cell · 1994 · 1.1K citations

Developmental Biology, Neurophysiology, Neuroanatomy +13

Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates

Ben‐Quan Shen, Keyang Xu, Luna Liu et al. · Nature Biotechnology · 2012 · 977 citations

Immunoengineering, Immunology, Bioconjugation +8