Inhibitory effects of wogonin on catalytic activity of cytochrome P450 enzyme in human liver microsomes

Pharmacogenetics of mephenytoin: A new drug hydroxylation polymorphism in man

A. K�pfer, R Preisig · European Journal of Clinical Pharmacology · 1984 · 363 citations

Pharmacology, Pharmacogenomics, Medicine

Wogonin, baicalin, and baicalein inhibition of inducible nitric oxide synthase and cyclooxygenase-2 gene expressions induced by nitric oxide synthase inhibitors and lipopolysaccharide11Abbreviations: NO, nitric oxide; iNOS, inducible nitricoxide synthase; COX-2, cyclooxygenase-2; PGE2,prostaglandin E2; MTT,3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide, LPS,lipopolysaccharide; NLA, N-nitro-l-arginine; andL-NAME, N-nitro-l-arginine methyl ester.

Yen‐Chou Chen, Shing‐Chuan Shen, Lih-Geeng Chen et al. · Biochemical Pharmacology · 2001 · 270 citations

Inhibitory Activity, Medicinal Chemistry, Biochemistry +12

Comparative pharmacokinetic interaction profiles of pravastatin, simvastatin, and atorvastatin when coadministered with cytochrome P450 inhibitors

Terry A. Jacobson · The American Journal of Cardiology · 2004 · 238 citations

Molecular Pharmacology, Cytochrome P450 Inhibitors, Pharmacological Study +5

St John's wort induces both cytochrome P450 3A4–catalyzed sulfoxidation and 2C19–dependent hydroxylation of omeprazole

Liansheng Wang, Gan Zhou, Bing Zhu et al. · Clinical Pharmacology & Therapeutics · 2004 · 144 citations

Probable Antagonism of Warfarin by Green Tea

James R. Taylor, Vickie M. Wilt · Annals of Pharmacotherapy · 1999 · 143 citations