Yen‐Chou Chen

Involvement of reactive oxygen species and caspase 3 activation in arsenite-induced apoptosis

Yen‐Chou Chen, Shoei‐Yn Lin‐Shiau, Jen‐Kun Lin · Journal of Cellular Physiology · 1998 · 472 citations

Oroxylin A inhibition of lipopolysaccharide-induced iNOS and COX-2 gene expression via suppression of nuclear factor-κB activation

Yen‐Chou Chen, Lingling Yang, Tony J-F Lee · Biochemical Pharmacology · 2000 · 325 citations

Inflammation, Cox-2 Gene Expression, Anti-inflammatory +9

Wogonin, baicalin, and baicalein inhibition of inducible nitric oxide synthase and cyclooxygenase-2 gene expressions induced by nitric oxide synthase inhibitors and lipopolysaccharide11Abbreviations: NO, nitric oxide; iNOS, inducible nitricoxide synthase; COX-2, cyclooxygenase-2; PGE2,prostaglandin E2; MTT,3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide, LPS,lipopolysaccharide; NLA, N-nitro-l-arginine; andL-NAME, N-nitro-l-arginine methyl ester.

Yen‐Chou Chen, Shing‐Chuan Shen, Lih-Geeng Chen et al. · Biochemical Pharmacology · 2001 · 270 citations

Inhibitory Activity, Medicinal Chemistry, Biochemistry +12

Quercetin, but not rutin and quercitrin, prevention of H2O2-induced apoptosis via anti-oxidant activity and heme oxygenase 1 gene expression in macrophages

Jyh‐Ming Chow, Shing‐Chuan Shen, Steven K. Huan et al. · Biochemical Pharmacology · 2005 · 237 citations

Inflammation, Heme Oxygenase 1, H2o2-induced Apoptosis +11

Wogonin and fisetin induction of apoptosis through activation of caspase 3 cascade and alternative expression of p21 protein in hepatocellular carcinoma cells SK-HEP-1

Yen‐Chou Chen, Shing‐Chuan Shen, W. Robert Lee et al. · Archives of Toxicology · 2002 · 170 citations

P21 Protein, Medicine, Liver Physiology +11