Cord blood CD4+CD25+ regulatory T cells fail to inhibit cord blood NK cell functions due to insufficient production and expression of TGF-beta1

Cell Contact–Dependent Immunosuppression by Cd4+Cd25+Regulatory T Cells Is Mediated by Cell Surface–Bound Transforming Growth Factor β

Kazuhiko Nakamura, Atsushi Kitani, Warren Strober · The Journal of Experimental Medicine · 2001 · 1.6K citations · Full text

Life Sciences, Cell Biology, Immunology +17

CD4<b>+</b>CD25<b>+</b> regulatory T cells inhibit natural killer cell functions in a transforming growth factor–β–dependent manner

François Ghiringhelli, Cédric Menard, Magali Terme et al. · The Journal of Experimental Medicine · 2005 · 919 citations · Full text

Life Sciences, Immunology, Oncology +17

CD4+CD25+ Regulatory T Cells Can Mediate Suppressor Function in the Absence of Transforming Growth Factor β1 Production and Responsiveness

Ciriaco A. Piccirillo, John J. Letterio, Angela M. Thornton et al. · The Journal of Experimental Medicine · 2002 · 595 citations · Full text

Life Sciences, Cell Biology, Immunology +17

IL-2 Is Essential for TGF-β to Convert Naive CD4+CD25− Cells to CD25+Foxp3+ Regulatory T Cells and for Expansion of These Cells

Song Guo Zheng, Juhua Wang, Pu Wang et al. · The Journal of Immunology · 2007 · 590 citations

Life Sciences, Immunology, Autoimmunity +14

Elevated TGF-β1 Secretion and Down-Modulation of NKG2D Underlies Impaired NK Cytotoxicity in Cancer Patients

June-Chul Lee, Kyung‐Mi Lee, Dong‐Wan Kim et al. · The Journal of Immunology · 2004 · 539 citations · Full text

Life Sciences, Immunology, Oncology +10