An investigation into the thermal behaviour of a model drug mixture with amorphous trehalose

Is trehalose special for preserving dry biomaterials?

Lois M. Crowe, David S. Reid, J.H. Crowe · Biophysical Journal · 1996 · 590 citations · Full text

Natural Sciences, Biochemistry, Biotechnology +10

Beneficial Effect of Intracellular Trehalose on the Membrane Integrity of Dried Mammalian Cells

Tani Chen, Jason P. Acker, Ali Eroğlu et al. · Cryobiology · 2001 · 195 citations

Life Sciences, Biochemistry, Cell Biology +17

The crystal structure of α,α-trehalose dihydrate from three independent X-ray determinations

G. M. Brown, D. C. Rohrer, B. Berking et al. · Acta Crystallographica Section B · 1972 · 143 citations

Natural Sciences, Biochemistry, Chemistry +16

Protein spray freeze drying. 2. Effect of formulation variables on particle size and stability

Henry R. Costantino, Laleh Firouzabadian, Chichih Wu et al. · Journal of Pharmaceutical Sciences · 2002 · 128 citations

Pharmacy, Food Science, Lyophilization +14

Polymorphic Amorphous and Crystalline Forms of Trehalose

Fabiana Sussich, Ranieri Urbani, Francesco Princivalle et al. · Journal of the American Chemical Society · 1998 · 111 citations

Pharmacy, Biochemistry, Chemistry +15