Association of CYP2D6 and CYP1A2 gene polymorphism with tardive dyskinesia in Chinese schizophrenic patients

Functional significance of a C→A polymorphism in intron 1 of the cytochrome P450 CYP1A2 gene tested with caffeine

Christoph Sachse, Jürgen Brockmöller, Steffen Bauer et al. · British Journal of Clinical Pharmacology · 1999 · 750 citations · Full text

Life Sciences, Genetics, Pharmacology +14

Genetic Polymorphism in the 5'-Flanking Region of HumanCYP1A2 Gene: Effect on the CYP1A2 Inducibility in Humans

Mitsutoshi Nakajima, Tsuyoshi Yokoi, Mayumi Mizutani et al. · The Journal of Biochemistry · 1999 · 347 citations

Medicine, Molecular Genetics, Pharmacology +12

Population distribution and effects on drug metabolism of a genetic variant in the 5′ promotor region of CYP3A4

S. Ball, JoAnn Scatina, John Y. Kao et al. · Clinical Pharmacology & Therapeutics · 1999 · 233 citations

Life Sciences, Genetics, Molecular Genetics +16

Caffeine as a metabolic probe: Exploration of the enzyme-inducing effect of cigarette smoking

W. Kalow, Bing-Kou Tang · Clinical Pharmacology & Therapeutics · 1991 · 218 citations

Medicine, Biochemistry, Toxicology +14

A functional polymorphism of the cytochrome P450 1A2 (CYP1A2) gene: association with tardive dyskinesia in schizophrenia

Vincenzo S. Basile, Vural Özdemir, Mario Masellis et al. · Molecular Psychiatry · 2000 · 169 citations

Medicine, Genetics, Pharmacology +16