A Novel Whole Exon Deletion in WWOX Gene Causes Early Epilepsy, Intellectual Disability and Optic Atrophy

A copy number variation morbidity map of developmental delay

Gregory M. Cooper, Bradley P. Coe, Santhosh Girirajan et al. · Nature Genetics · 2011 · 1.4K citations · Full text

Medicine, Genetics, Cognitive Development +6

WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer.

Andrzej K. Bednarek, K J Laflin, Rachael Daniel et al. · PubMed · 2000 · 428 citations

Breast Oncology, Genetics, Molecular Biology +20

WWOX, the FRA16D gene, behaves as a suppressor of tumor growth.

Andrzej K. Bednarek, C.L. Keck-Waggoner, Rachael Daniel et al. · PubMed · 2001 · 277 citations

Radiation Oncology, Breast Oncology, Medicine +14

Quantification of Homozygosity in Consanguineous Individuals with Autosomal Recessive Disease

C. Geoffrey Woods, James J. Cox, Kelly Springell et al. · The American Journal of Human Genetics · 2006 · 264 citations · Full text

Mendelian Disorder, Genetic Disorder, Medicine +9

Targeted deletion of <i>Wwox</i> reveals a tumor suppressor function

Rami I. Aqeilan, Francesco Trapasso, Sadiq Hussain et al. · Proceedings of the National Academy of Sciences · 2007 · 208 citations · Full text