Concepedia

The methodological approach for the generation of humandendritic cells from monocytes affects the maturation state of the resultant dendritic cells

I Mucci, Annalisa Legitimo, M Compagnino, Rita Consolini, Pasquale Migliaccio, Maria Rita Metelli, Fabrizio Scatena

Biologicals · 2009 · 25 citations · 24 references

DOI

Concepts

References

24

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.

Federica Sallusto, Antonio Lanzavecchia · The Journal of Experimental Medicine · 1994 · 5.2K citations · Full text

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Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products.

Federica Sallusto, Marina Cella, Carlo Danieli et al. · The Journal of Experimental Medicine · 1995 · 2.5K citations · Full text

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Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation.

Marina Cella, Doris Scheidegger, Kathrin Palmer-Lehmann et al. · The Journal of Experimental Medicine · 1996 · 2K citations · Full text

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High gradient magnetic cell separation with MACS

Stefan Miltenyi, Werner Müller, Walter Weichel et al. · Cytometry · 1990 · 1.7K citations

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Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells.

S E Macatonia, Nancy Hosken, Mark J. Litton et al. · The Journal of Immunology · 1995 · 1.5K citations

, , +17