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Actions Underlying Antidiabetic Effects of Ocimum sanctum Leaf Extracts in Animal Models of Type 1 and Type 2 Diabetes

J. M. A. Hannan, Opeolu O. Ojo, J. Khaleque, Masfida Akhter, Peter R. Flatt, Yasser H.A. Abdel‐Wahab

European Journal of Medicinal Plants · 2014 · 29 citations · 26 references

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Abstract

Aim: This study investigated mechanisms by which O. sanctum leaf extracts ameliorate hyperglycaemia using animal and cellular models of diabetes.

References

26

The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas

Tomasz Szkudelski · Physiological Research · 2001 · 2.9K citations · Full text

, , +13

Evidence for the involvement of vicinal sulfhydryl groups in insulin-activated hexose transport by 3T3-L1 adipocytes.

Susan C. Frost, M. Daniel Lane · Journal of Biological Chemistry · 1985 · 513 citations · Full text

, , +17

Antioxidant and cyclooxygenase inhibitory phenolic compounds from Ocimum sanctum Linn.

Mark A. Kelm, Muraleedharan G. Nair, Gale M. Strasburg et al. · Phytomedicine · 2000 · 429 citations

, , +13

Responses of Neonatal Rat Islets to Streptozotocin: Limited B-Cell Regeneration and Hyperglycemia

Susan Bonner‐Weir, David Trent, Richard N. Honey et al. · Diabetes · 1981 · 311 citations

, , +17

Insulin receptors in β-cells are critical for islet compensatory growth response to insulin resistance

Terumasa Okada, Chong Wee Liew, Jiang Hu et al. · Proceedings of the National Academy of Sciences · 2007 · 285 citations · Full text

, , +17