Hydrophobic and Ionic Factors in the Binding of Local Anesthetics to the Major Variant of Human α1-Acid Glycoprotein

Fundamental Properties of Local Anesthetics. II. Measured Octanol

Gary R. Strichartz, Virgil Sanchez, G. Richard Arthur et al. · Anesthesia & Analgesia · 1990 · 289 citations

Medicine, Anesthesiology, Pharmacology +15

The plasma protein binding of basic drugs.

PA Routledge · British Journal of Clinical Pharmacology · 1986 · 181 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Plasma drug binding: implications for anesthesiologists.

Margaret Wood · PubMed · 1986 · 154 citations

Medicine, Anesthesiology, Pharmacology +11

Ligand Specificity of the Genetic Variants of Human α1-Acid Glycoprotein: Generation of a Three-Dimensional Quantitative Structure-Activity Relationship Model for Drug Binding to the A Variant

Françoise Hervé, Giulia Caron, Jean-Claude Duché et al. · Molecular Pharmacology · 1998 · 104 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

Plasma Drug Binding

Margaret Wood · Anesthesia & Analgesia · 1986 · 80 citations

Medicine, Pharmacology, Anesthesia +4