Concepedia

Plasma Protein Binding Differences

Plasma Protein Binding Differences is a toxicokinetic phenomenon that refers to the interspecies variation in the extent and affinity with which drugs or toxins bind to plasma proteins, thereby influencing their distribution, free concentration, and elimination.

285

Publications

13.1K

Citations

932

Authors

290

Institutions

Publications per year

2017–2026

9

Variants

Interspecies Plasma Protein Binding Differences

Parents

Publications

285

The Clinical Relevance of Plasma Protein Binding Changes

Jason A. Roberts, Federico Pea, Jeffrey Lipman · Clinical Pharmacokinetics · 2012 · 325 citations · Full text

, , +14

Increased Plasma Protein Binding of Propranolol and Chlorpromazine Mediated by Disease-Induced Elevations of Plasma α<sub>1</sub>Acid Glycoprotein

Kenneth M. Piafsky, Ingegerd Odar‐Cederlöf, C. Johansson et al. · New England Journal of Medicine · 1978 · 293 citations

, , +15

Age differences in drug binding by plasma proteins: Studies on human foetuses, neonates and adults

M. Ehrnebo, Stig Agurell, Birgitta Jalling et al. · European Journal of Clinical Pharmacology · 1971 · 266 citations

, , +14

Effect of Altered Plasma Protein Binding on Apparent Volume of Distribution

Svein Øie, Thomas N. Tozer · Journal of Pharmaceutical Sciences · 1979 · 255 citations

, , +13

Isomer-Specific Binding Affinity of Perfluorooctanesulfonate (PFOS) and Perfluorooctanoate (PFOA) to Serum Proteins

Sanjay Beesoon, Jonathan W. Martin · Environmental Science & Technology · 2015 · 221 citations

, , +15

1–5 of 285

Authors

932

  1. GL
    Gerhard Levy

    University at Buffalo, State University of New York, United States

    6 publications · 231 citations

    6

    h-index

  2. JT
    Jean‐Paul Tillement

    Université Paris-Est Créteil, France

    5 publications · 239 citations

    5

    h-index

  3. FS
    Folke Sjöqvist

    Karolinska Institutet, Sweden

    4 publications · 419 citations

    4

    h-index

  4. PR
    PA Routledge

    University Hospital Llandough, United Kingdom

    4 publications · 265 citations

    4

    h-index

  5. RK
    Roger K. Verbeeck

    UCLouvain, Belgium

    4 publications · 241 citations

    4

    h-index

1–5 of 932

Institutions

290

  1. University at Buffalo, State University of New York

    Buffalo, United States

    10 h-index

    26 publications

    977 citations

  2. Université Paris-Est Créteil

    Créteil, France

    6 h-index

    23 publications

    703 citations

  3. The University of Queensland

    Brisbane, Australia

    5 h-index

    11 publications

    1.7K citations

  4. University of Florida

    Gainesville, United States

    4 h-index

    14 publications

    454 citations

  5. University of Tennessee at Knoxville

    Knoxville, United States

    4 h-index

    10 publications

    739 citations

  6. National Institutes of Health

    Bethesda, United States

    4 h-index

    13 publications

    225 citations

  7. Hôpital Intercommunal de Créteil

    Créteil, France

    4 h-index

    14 publications

    798 citations

  8. Karolinska University Hospital

    Stockholm, Sweden

    4 h-index

    16 publications

    1.6K citations

1–8 of 290

Venues

  1. Clinical Pharmacology & Therapeutics

    CPT · 27 publications · 1.8K citations

    23

    h-index

  2. British Journal of Clinical Pharmacology

    BJCP · 23 publications · 933 citations

    19

    h-index

  3. Journal of Pharmacy and Pharmacology

    JPP · 16 publications · 583 citations

    14

    h-index

  4. PubMed

    Repository · 16 publications · 700 citations

    13

    h-index

  5. Journal of Pharmaceutical Sciences

    14 publications · 808 citations

    12

    h-index

1–5