Concepedia

2-(3-<i>tert</i>-Butyldimethylsiloxy-4-methoxyphenyl)-6-methoxy-3-(3,4,5-trimethoxybenzoyl)indole

Mallinath B. Hadimani, Raymond J. Kessler, J.A. Kautz, Anjan Ghatak, Anupama Shirali, Heather O’Dell, C. Michael Garner, Kevin G. Pinney

Acta Crystallographica Section C Crystal Structure Communications · 2002 · 15 citations · 9 references

DOI

Concepts

Abstract

In the crystal structure of the title compound, C(32)H(39)NO(7)Si, all geometric parameters fall within experimental error of expected values. The analysis of molecular-packing plots reveals an infinite two-dimensional linear array running parallel to the b axis, formed by one N[bond]H...O intermolecular hydrogen-bonding interaction. Several potential C[bond]H...O interactions are also present.

References

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The synthesis and tubulin binding activity of thiophene-based analogues of combretastatin A-4

Bernard L. Flynn, Guy P. Flynn, Ernest Hamel et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 140 citations · Full text

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